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Nat’s Pancreas 404 🐝 #COVIDisAirborne

@1derfultype

Sep 23

14 tweets
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Betting for the next best thing in digital #diabetes technology: '#AID systems & algorithms are very effective. Unfortunately, they are used by a minority of ppl who cld benefit from them.' -Steven Russell #EASD2022 #dedoc°voices #nothingaboutuswithoutus @#dedoc° 1/n

Betting for the next best thing in digital #diabetes technology: 'In addition to the challenges of getting hybrid #AID systems, they still require setups. They still require the user to #carbcount for meals & initiate correction boluses.' -Steven Russell #EASD2022 #dedoc 2/n

Betting for the next best thing in digital #diabetes technology: 'The #IletBionicPancreas pivotal trial results will be published by end Sept.' -Steven Russell ✅ Only setup needed: @Kai Tian's weight ✅ No #carbcounting ✅ Fully automated #EASD2022 #dedoc°voices #BetaBionics 3/n

Betting for the next best thing in digital #diabetes technology: 'The 13 wks #IletBionicPancreas pivotal trial results will be published by end Sept.' -Steven Russell ✅ 26% minority population ⬆️ +16% #TIR ⬇️ -0.5% #A1c #EASD2022 #dedoc°voices #diabetesadvocacy @#dedoc° 4/n

Betting for the next best thing in digital #diabetes technology: 'Similar results with #ControlIQ studies whereas the #IletBionicPancreas doesn't require carb counting and insulin parameters.' -Steven Russell It looks promising ✨ #EASD2022 #dedoc°voices #payitforward 5/n

Betting for the next best thing in digital #diabetes technology: 2 faster insulins #Fiasp & #Lyumjev have: ✅ 15-25min shortened time of peak ⬇️ postprandial #BG ⬇️ mean #BG ↔️ #TIR #EASD2022 #dedoc°voices #nothingaboutuswithoutus #diabetesadvocacy @EASD @#dedoc° 6/n

Betting for the next best thing in digital #diabetes technology: 'With faster insulin, we can clamp the #BG within a very narrow range.' 👇 -Steven Russell ✅ Mean BG in #T1D group: 107mg ✅ Range: 96-128mg ✅ #TIR: 98% ✅ No hypo #EASD2022 #dedoc°voices @#dedoc° 7/n

Betting for the next best thing in digital #diabetes technology: 'Glucagon could take us further. 2 hormones are missing in #T1D: ❌ #insulin beta cells ❌ #glucagon alpha cells are there but no longer respond to hypo.' -Steven Russell #EASD2022 #dedoc°voices @#dedoc° 8/n

Betting for the next best thing in digital #diabetes technology: '#glucagon is the most important defence against #hypo ➡️ automatic microdosing of glucagon may prevent severity of hypo as it is absorbed much faster than #insulin.' -Steven Russell #EASD2022 #dedoc @#dedoc° 9/n

Betting for the next best thing in digital #diabetes technology: 7-day #IletBionicPancreas study: Insulin only ▶️ 72% #TIR Bi-hormonal ▶️ 79% #TIR & less hypo 'We now have a stable #glucagon analog: Zegalogue (Dasiglucagon).' -Steven Russell #EASD2022 #dedoc° 10/n

Betting for the next best thing in digital #diabetes technology: 'In the future, we may have glucose-responsive #insulin that only acts when the glucose is high and is prevented from acting when low.' -Steven Russell #EASD2022 #dedoc°voices #DOC @EASD @#dedoc° 11/n

Betting for the next best thing in digital #diabetes technology: 'Possible adjunct therapies to #AID: ✅ Pramlintide ✅ GLP-1 agonists ✅ SGLT-2 inhibitors' -Steven Russell #EASD2022 #dedoc°voices @EASD @#dedoc° 12/n

Betting for the next best thing in digital #diabetes technology: Ideal bihormonal #ClosedLoop system: ✅ Automated #glucagon ✅ Smart #insulin ✅ Adjunct drugs The device has been submitted to the FDA - not yet to Europe 😭 #EASD2022 #dedoc°voices @#dedoc° 13/n

Hey @Thread Reader App, pls unroll this 🧵 🙏🙏🙏

Nat’s Pancreas 404 🐝 #COVIDisAirborne

@1derfultype

Type 1 circa 1983 | Empowered by the #DOC #WeAreNotWaiting #LanguageMatters #NothingAboutUsWithoutUs | #Type1EU & #dedoc°voices | Own views - She/Her

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