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Anthony J Leonardi, PhD, MS

Anthony J Leonardi, PhD, MS
@fitterhappierAJ

Mar 18, 2022
7 tweets
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wow sars cov 2 is killing T cells nature.com/articles/s4141

Cell Death & Differentiation - T cell apoptosis characterizes severe Covid-19 disease
nature.com/articles/s4141…
T cell apoptosis characterizes severe Covid-19 disease
wow sars cov 2 causes more acute apoptosis than HIV biorxiv.org/content/10.110 (actually I'm not surprised, I expected this) twitter.com/fitterhappierA
Anthony J Leonardi, PhD, MS

Anthony J Leonardi, PhD, MS
@fitterhappierAJ

Sep 15 20
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If the infection destroys b cell memory formation with TNF and wrecks cd8 t cells with cd95- it harms memory twitter.com/fitterhappierA
Holy Moly sars cov 2 is causing T cell mediated autoimmunity in an unprecedented mechanism! frontiersin.org/articles/10.33
Severe COVID-19 patients show various immunological abnormalities including T-cell reduction and cytokine release syndrome, which can be fatal and is a major concern of the pandemic. However, it is...
frontiersin.org/articles/10.33…
T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis
Severe COVID-19 patients show various immunological abnormalities including T-cell reduction and cytokine release syndrome, which can be fatal and is a major concern of the pandemic. However, it is...
Holy moly cd8 t cells causing PASC/ long covid! science.org/doi/10.1126/sc
Respiratory tissue resident–like CD8+ T cells are associated with chronic lung sequelae post-acute COVID-19.
science.org/doi/10.1126/sc…
Immune signatures underlying post-acute COVID-19 lung sequelae
Respiratory tissue resident–like CD8+ T cells are associated with chronic lung sequelae post-acute COVID-19.
Oh wow T cells go to your brain in sars cov 2 infection but not in flu!
Maybe steroids work in part by dampening T cell responses huh? but this is more clinical knowledge than path ;)
My word sars cov 2 is getting rid of naive t cells nature.com/articles/s4159 (i am not surprised) twitter.com/fitterhappierA
Anthony J Leonardi, PhD, MS

Anthony J Leonardi, PhD, MS
@fitterhappierAJ

Aug 22 20
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and recall that covid survivors have a relative lymphopenia. kiss much of your naive t cells goodbye.
Anthony J Leonardi, PhD, MS

Anthony J Leonardi, PhD, MS

@fitterhappierAJ
PhD (T cell differentiation) BS MS MPH (student) @JohnsHopkins 2022 Kavli Fellow Honorary Research Fellow Views own https://t.co/AA6klJUBZ8
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