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Johanna Gassler

Johanna Gassler
@johanna_gassler

Nov 24
7 tweets
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How is the embryonic chromatin activated? science.org/doi/10.1126/sc… I am happy to share our findings on how Nr5a2 acts as a pioneer factor during the murine zygotic genome activation @Science Magazine #ScienceResearch Together with @Wataru Kobayashi, @Siwat Chad & Imre Gáspár.

2/6 For a detailed description of our findings, please see our previous Twitter threads on the preprint linked below: twitter.com/johanna_gassle…
Johanna Gassler

Johanna Gassler
@johanna_gassler

Which factors are regulating the awakening of the genome in totipotent mouse embryos? biorxiv.org/content/10.110… Just in time for the #EMBOmzt! I am happy to finally share the latest research findings from our lab with @Wataru Kobayashi, @Siwat Chad & the twitterless Imre Gáspár. 1/6
3/6 Focus on the biochemical characterization as a pioneer factor: twitter.com/WataKobayashi/…
4/6 This work was a great collaborative effort in our lab, and I am grateful to all my colleagues, and especially Kikuë, for providing us with the environment and resources to work on it as a team. This work was done @Max Planck Institute of Biochemistry (MPIB) and @IMBA
5/6 It has been amazing to see this project develop and take shape. I worked on it from the very first idea and questions we formulated to the current version - the longest time I've ever worked on a research project.
6/6 In the end, I am happy to say that I have many more questions than when I started, which opens up exciting possibilities for future research.
Last but not least: The copyright of the graphic shown in the first tweet belongs to: Max Iglesias/MPIB Was a really cool experience, would definitely highly recommend working with Max!
Johanna Gassler

Johanna Gassler

@johanna_gassler
Chromatin Organisation - Epigenetic (Re)Programming - Totipotency PhD Student
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