A couple of weeks ago I reviewed the BA.5 bivalent booster data and concluded it has worked better than expected
erictopol.substack.com/p/the-bivalent…
Today there are 3 new reports that strongly reinforce that
1. Comparing bivalent vs original for protection vs hospitalizations & deaths
2. Superior neutralizing antibodies vs the new variants with marked immune evasion: XBB.1, BQ.1.1, BA.2.75 compared with the original booster (adds to 12 lab studies)
3. Higher protection vs symptomatic infections (against XBB.1.5, which has an extreme ° of immune escape) than has been seen for the original booster, for at least 3 months
[Original booster vs Omicron lineages ≤ 30% protection, and short-lived]